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The regulation of TGF-β/SMAD signaling by protein deubiquitination

Transforming growth factor-β (TGF-β) members are key cytokines that control embryogenesis and tissue homeostasis via transmembrane TGF-β type II (TβR II) and type I (TβRI) and serine/threonine kinases receptors. Aberrant activation of TGF-β signaling leads to diseases, including cancer. In advanced...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Zhang, Xiaofei, Xie, Feng, Zhang, Zhengkui, van Dam, Hans, Zhang, Long, Zhou, Fangfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085288/
https://www.ncbi.nlm.nih.gov/pubmed/24756567
http://dx.doi.org/10.1007/s13238-014-0058-8