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New approaches to the management of schizophrenia: focus on aberrant hippocampal drive of dopamine pathways
Schizophrenia is a disease affecting up to 1% of the population. Current therapies are based on the efficacy of chlorpromazine, discovered over 50 years ago. These drugs block dopamine D2-like receptors and are effective at primarily treating positive symptoms in a subset of patients. Unfortunately,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085299/ https://www.ncbi.nlm.nih.gov/pubmed/25061280 http://dx.doi.org/10.2147/DDDT.S42708 |