Conservation in first introns is positively associated with the number of exons within genes and the presence of regulatory epigenetic signals

BACKGROUND: Genomes of higher eukaryotes have surprisingly long first introns and in some cases, the first introns have been shown to have higher conservation relative to other introns. However, the functional relevance of conserved regions in the first introns is poorly understood. Leveraging the r...

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Detalles Bibliográficos
Autores principales: Park, Seung Gu, Hannenhalli, Sridhar, Choi, Sun Shim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085337/
https://www.ncbi.nlm.nih.gov/pubmed/24964727
http://dx.doi.org/10.1186/1471-2164-15-526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085337/
https://www.ncbi.nlm.nih.gov/pubmed/24964727
http://dx.doi.org/10.1186/1471-2164-15-526

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