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Conservation in first introns is positively associated with the number of exons within genes and the presence of regulatory epigenetic signals
BACKGROUND: Genomes of higher eukaryotes have surprisingly long first introns and in some cases, the first introns have been shown to have higher conservation relative to other introns. However, the functional relevance of conserved regions in the first introns is poorly understood. Leveraging the r...
Autores principales: | Park, Seung Gu, Hannenhalli, Sridhar, Choi, Sun Shim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085337/ https://www.ncbi.nlm.nih.gov/pubmed/24964727 http://dx.doi.org/10.1186/1471-2164-15-526 |
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