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Ascorbylperoxide from parenteral nutrition induces an increase of redox potential of glutathione and loss of alveoli in newborn guinea pig lungs

BACKGROUND: Bronchopulmonary dysplasia is one of the main complications associated with extreme prematurity. Oxidative stress is suspected to be a trigger event of this lung disease, which is characterized by impaired alveolar development. Peroxides, mainly ascorbylperoxide and H(2)O(2), are known c...

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Detalles Bibliográficos
Autores principales: Elremaly, Wesam, Mohamed, Ibrahim, Mialet-Marty, Tiphaine, Rouleau, Thérèse, Lavoie, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085348/
https://www.ncbi.nlm.nih.gov/pubmed/25009773
http://dx.doi.org/10.1016/j.redox.2014.05.002