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Zn/Ga−DFO iron–chelating complex attenuates the inflammatory process in a mouse model of asthma

BACKGROUND: Redox-active iron, a catalyst in the production of hydroxyl radicals via the Fenton reaction, is one of the key participants in ROS-induced tissue injury and general inflammation. According to our recent findings, an excess of tissue iron is involved in several airway-related pathologies...

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Detalles Bibliográficos
Autores principales: Bibi, Haim, Vinokur, Vladimir, Waisman, Dan, Elenberg, Yigal, Landesberg, Amir, Faingersh, Anna, Yadid, Moran, Brod, Vera, Pesin, Jimy, Berenshtein, Eduard, Eliashar, Ron, Chevion, Mordechai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085351/
https://www.ncbi.nlm.nih.gov/pubmed/25009783
http://dx.doi.org/10.1016/j.redox.2014.06.009