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Zn/Ga−DFO iron–chelating complex attenuates the inflammatory process in a mouse model of asthma
BACKGROUND: Redox-active iron, a catalyst in the production of hydroxyl radicals via the Fenton reaction, is one of the key participants in ROS-induced tissue injury and general inflammation. According to our recent findings, an excess of tissue iron is involved in several airway-related pathologies...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085351/ https://www.ncbi.nlm.nih.gov/pubmed/25009783 http://dx.doi.org/10.1016/j.redox.2014.06.009 |