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Retroviral-infection increases tumorigenic potential of MDA-MB-231 breast carcinoma cells by expanding an aldehyde dehydrogenase (ALDH1) positive stem-cell like population

Retroviral transformation has been associated with pro-proliferative oncogenic signaling in human cells. The current study demonstrates that transduction of human breast carcinoma cells (MDA-MB231) with LXSN and QCXIP retroviral vectors causes significant increases in growth rate, clonogenic fractio...

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Detalles Bibliográficos
Autores principales: Wegman-Points, Lauren J., Teoh-Fitzgerald, Melissa L.T., Mao, Gaowei, Zhu, Yueming, Fath, Melissa A., Spitz, Douglas R., Domann, Frederick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085353/
https://www.ncbi.nlm.nih.gov/pubmed/25009786
http://dx.doi.org/10.1016/j.redox.2014.06.006