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Retroviral-infection increases tumorigenic potential of MDA-MB-231 breast carcinoma cells by expanding an aldehyde dehydrogenase (ALDH1) positive stem-cell like population
Retroviral transformation has been associated with pro-proliferative oncogenic signaling in human cells. The current study demonstrates that transduction of human breast carcinoma cells (MDA-MB231) with LXSN and QCXIP retroviral vectors causes significant increases in growth rate, clonogenic fractio...
Autores principales: | Wegman-Points, Lauren J., Teoh-Fitzgerald, Melissa L.T., Mao, Gaowei, Zhu, Yueming, Fath, Melissa A., Spitz, Douglas R., Domann, Frederick E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085353/ https://www.ncbi.nlm.nih.gov/pubmed/25009786 http://dx.doi.org/10.1016/j.redox.2014.06.006 |
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