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Terminate and make a loop: regulation of transcriptional directionality

Bidirectional promoters are a common feature of many eukaryotic organisms from yeast to humans. RNA Polymerase II that is recruited to this type of promoter can start transcribing in either direction using alternative DNA strands as the template. Such promiscuous transcription can lead to the synthe...

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Detalles Bibliográficos
Autores principales: Grzechnik, Pawel, Tan-Wong, Sue Mei, Proudfoot, Nick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Trends Journals 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085477/
https://www.ncbi.nlm.nih.gov/pubmed/24928762
http://dx.doi.org/10.1016/j.tibs.2014.05.001