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Differential sensitivity of Glioma stem cells to Aurora kinase A inhibitors: Implications for stem cell mitosis and centrosome dynamics

Glioma stem-cell-like cells are considered to be responsible for treatment resistance and tumour recurrence following chemo-radiation in glioblastoma patients, but specific targets by which to kill the cancer stem cell population remain elusive. A characteristic feature of stem cells is their abilit...

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Detalles Bibliográficos
Autores principales: Mannino, Mariella, Gomez-Roman, Natividad, Hochegger, Helfrid, Chalmers, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085484/
https://www.ncbi.nlm.nih.gov/pubmed/24879067
http://dx.doi.org/10.1016/j.scr.2014.05.001