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Differential sensitivity of Glioma stem cells to Aurora kinase A inhibitors: Implications for stem cell mitosis and centrosome dynamics
Glioma stem-cell-like cells are considered to be responsible for treatment resistance and tumour recurrence following chemo-radiation in glioblastoma patients, but specific targets by which to kill the cancer stem cell population remain elusive. A characteristic feature of stem cells is their abilit...
Autores principales: | Mannino, Mariella, Gomez-Roman, Natividad, Hochegger, Helfrid, Chalmers, Anthony J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085484/ https://www.ncbi.nlm.nih.gov/pubmed/24879067 http://dx.doi.org/10.1016/j.scr.2014.05.001 |
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