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Tumor cell-activated CARD9 signaling contributes to metastasis-associated macrophage polarization
Macrophages are critical immune effector cells of the tumor microenvironment that promote seeding, extravasation and persistent growth of tumor cells in primary tumors and metastatic sites. Tumor progression and metastasis are affected by dynamic changes in the specific phenotypes of macrophage subp...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085533/ https://www.ncbi.nlm.nih.gov/pubmed/24722209 http://dx.doi.org/10.1038/cdd.2014.45 |