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Preliminary Studies on Validation of Calu-3 Cell Line as a Model for Screening Respiratory Mucosa Irritation and Toxicity

There is need to develop reproducible methods and experimental models for screening mucosal irritation and toxicity for drugs and pharmaceutical excipients. The aim of this study was to validate Calu-3 cell line as a model for screening respiratory irritation and toxicity of drugs and excipients. Ei...

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Detalles Bibliográficos
Autores principales: Ihekwereme, Chibueze, Esimone, Charles, Shao, Di, Agu, Remigius U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085599/
https://www.ncbi.nlm.nih.gov/pubmed/24962675
http://dx.doi.org/10.3390/pharmaceutics6020268