E3 Ligase Subunit Fbxo15 and PINK1 Kinase Regulate Cardiolipin Synthase 1 Stability and Mitochondrial Function in Pneumonia

Acute lung injury (ALI) is linked to mitochondrial injury, resulting in impaired cellular oxygen utilization; however, it is unknown how these events are linked on the molecular level. Cardiolipin, a mitochondrial-specific lipid, is generated by cardiolipin synthase (CLS1). Here, we show that S. aur...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Bill B., Coon, Tiffany A., Glasser, Jennifer R., Zou, Chunbin, Ellis, Bryon, Das, Tuhin, McKelvey, Alison C., Rajbhandari, Shristi, Lear, Travis, Kamga, Christelle, Shiva, Sruti, Li, Chenjian, Pilewski, Joseph M., Callio, Jason, Chu, Charleen T., Ray, Anuradha, Ray, Prabir, Tyurina, Yulia Y., Kagan, Valerian E., Mallampalli, Rama K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085683/
https://www.ncbi.nlm.nih.gov/pubmed/24703837
http://dx.doi.org/10.1016/j.celrep.2014.02.048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085683/
https://www.ncbi.nlm.nih.gov/pubmed/24703837
http://dx.doi.org/10.1016/j.celrep.2014.02.048

Ejemplares similares