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Open label smoking cessation with varenicline is associated with decreased glutamate levels and functional changes in anterior cingulate cortex: preliminary findings

Rationale: Varenicline, the most effective single agent for smoking cessation, is a partial agonist at α4β2 nicotinic acetylcholine receptors. Increasing evidence implicates glutamate in the pathophysiology of addiction and one of the benefits of treatment for smoking cessation is the ability to reg...

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Detalles Bibliográficos
Autores principales: Wheelock, Muriah D., Reid, Meredith A., To, Harrison, White, David M., Cropsey, Karen L., Lahti, Adrienne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085720/
https://www.ncbi.nlm.nih.gov/pubmed/25071576
http://dx.doi.org/10.3389/fphar.2014.00158