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Redefining the modular organization of the core Mediator complex

The Mediator complex plays an essential role in the regulation of eukaryotic transcription. The Saccharomyces cerevisiae core Mediator comprises 21 subunits, which are organized into Head, Middle and Tail modules. Previously, the Head module was assigned to a distinct dense domain at the base, and t...

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Detalles Bibliográficos
Autores principales: Wang, Xuejuan, Sun, Qianqian, Ding, Zhenrui, Ji, Jinhua, Wang, Jianye, Kong, Xiao, Yang, Jianghong, Cai, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085763/
https://www.ncbi.nlm.nih.gov/pubmed/24810298
http://dx.doi.org/10.1038/cr.2014.64