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DISC1 knockdown impairs the tangential migration of cortical interneurons by affecting the actin cytoskeleton

Disrupted-in-Schizophrenia 1 (DISC1) is a risk gene for a spectrum of major mental disorders. It has been shown to regulate radial migration as well as dendritic arborization during neurodevelopment and corticogenesis. In a previous study we demonstrated through in vitro experiments that DISC1 also...

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Detalles Bibliográficos
Autores principales: Steinecke, André, Gampe, Christin, Nitzsche, Falk, Bolz, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086047/
https://www.ncbi.nlm.nih.gov/pubmed/25071449
http://dx.doi.org/10.3389/fncel.2014.00190