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PTHGRN: unraveling post-translational hierarchical gene regulatory networks using PPI, ChIP-seq and gene expression data
Interactions among transcriptional factors (TFs), cofactors and other proteins or enzymes can affect transcriptional regulatory capabilities of eukaryotic organisms. Post-translational modifications (PTMs) cooperate with TFs and epigenetic alterations to constitute a hierarchical complexity in trans...
Autores principales: | Guan, Daogang, Shao, Jiaofang, Zhao, Zhongying, Wang, Panwen, Qin, Jing, Deng, Youping, Boheler, Kenneth R., Wang, Junwen, Yan, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086064/ https://www.ncbi.nlm.nih.gov/pubmed/24875471 http://dx.doi.org/10.1093/nar/gku471 |
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