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TSpred: a web server for the rational design of temperature-sensitive mutants

Temperature sensitive (Ts) mutants of proteins provide experimentalists with a powerful and reversible way of conditionally expressing genes. The technique has been widely used in determining the role of gene and gene products in several cellular processes. Traditionally, Ts mutants are generated by...

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Detalles Bibliográficos
Autores principales: Tan, Kuan Pern, Khare, Shruti, Varadarajan, Raghavan, Madhusudhan, Mallur Srivatsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086094/
https://www.ncbi.nlm.nih.gov/pubmed/24782523
http://dx.doi.org/10.1093/nar/gku319