Cargando…

PASTA 2.0: an improved server for protein aggregation prediction

The formation of amyloid aggregates upon protein misfolding is related to several devastating degenerative diseases. The propensities of different protein sequences to aggregate into amyloids, how they are enhanced by pathogenic mutations, the presence of aggregation hot spots stabilizing pathologic...

Descripción completa

Detalles Bibliográficos
Autores principales: Walsh, Ian, Seno, Flavio, Tosatto, Silvio C.E., Trovato, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086119/
https://www.ncbi.nlm.nih.gov/pubmed/24848016
http://dx.doi.org/10.1093/nar/gku399