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Postnatal maintenance of the 5-Ht1a-Pet1 autoregulatory loop by serotonin in the raphe nuclei of the brainstem

BACKGROUND: Despite the importance of 5-HT1A as a major target for the action of several anxiolytics/antidepressant drugs, little is known about its regulation in central serotonin (5-hydroxytryptamine, 5-HT) neurons. RESULTS: We report that expression of 5-HT1A and the transcription factor Pet1 was...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Young, Kim, Ana, Zhao, Zhong-Qiu, Liu, Xian-Yu, Chen, Zhou-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086287/
https://www.ncbi.nlm.nih.gov/pubmed/24972638
http://dx.doi.org/10.1186/1756-6606-7-48