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Inflammasomes: Molecular Regulation and Implications for Metabolic and Cognitive Diseases

Inflammasomes are specialized signaling platforms critical for the regulation of innate immune and inflammatory responses. Various NLR family members (i.e., NLRP1, NLRP3, and IPAF) as well as the PYHIN family member AIM2 can form inflammasome complexes. These multi-protein complexes activate inflamm...

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Detalles Bibliográficos
Autores principales: Choi, Alexander J.S., Ryter, Stefan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086337/
https://www.ncbi.nlm.nih.gov/pubmed/24850149
http://dx.doi.org/10.14348/molcells.2014.0104