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Circulating Levels of Sirtuin 4, a Potential Marker of Oxidative Metabolism, Related to Coronary Artery Disease in Obese Patients Suffering from NAFLD, with Normal or Slightly Increased Liver Enzymes

The present study shows low circulating levels of SIRT4 in obese patients with nonalcoholic fatty liver disease mirroring its reduced mitochondrial expression in an attempt to increase the fat oxidative capacity and then the mitochondrial function in liver and in muscle. SIRT4 modulates the metaboli...

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Detalles Bibliográficos
Autores principales: Tarantino, Giovanni, Finelli, Carmine, Scopacasa, Franco, Pasanisi, Fabrizio, Contaldo, Franco, Capone, Domenico, Savastano, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086623/
https://www.ncbi.nlm.nih.gov/pubmed/25045415
http://dx.doi.org/10.1155/2014/920676