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Elucidating the role of free polycationic chains in polycation gene carriers by free chains of polyethylenimine or N,N,N-trimethyl chitosan plus a certain polyplex

Polycations as gene carriers have attracted considerable attention over the past decade. Generally, polyplexes between polycations and deoxyribonucleic acid (DNA) are formed at low N/P ratios (the ratios of the numbers of nitrogen atoms in a polycation to the numbers of phosphorus atoms in DNA), but...

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Detalles Bibliográficos
Autores principales: Xu, Tao, Liu, Wei, Wang, Suhang, Shao, Zhengzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086671/
https://www.ncbi.nlm.nih.gov/pubmed/25061299
http://dx.doi.org/10.2147/IJN.S64308