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Cerebrospinal fluid metabolomics reveals altered waste clearance and accelerated aging in HIV patients with neurocognitive impairment

OBJECTIVE(S): HIV-associated neurocognitive disorders (HAND) remain prevalent in HIV-infected patients on antiretroviral therapy (ART), but the underlying mechanisms are unclear. Some features of HAND resemble those of age-associated cognitive decline in the absence of HIV, suggesting that overlappi...

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Detalles Bibliográficos
Autores principales: Cassol, Edana, Misra, Vikas, Dutta, Anupriya, Morgello, Susan, Gabuzda, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086755/
https://www.ncbi.nlm.nih.gov/pubmed/24752083
http://dx.doi.org/10.1097/QAD.0000000000000303