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Non-associative Potentiation of Perisomatic Inhibition Alters the Temporal Coding of Neocortical Layer 5 Pyramidal Neurons

In the neocortex, the coexistence of temporally locked excitation and inhibition governs complex network activity underlying cognitive functions, and is believed to be altered in several brain diseases. Here we show that this equilibrium can be unlocked by increased activity of layer 5 pyramidal neu...

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Detalles Bibliográficos
Autores principales: Lourenço, Joana, Pacioni, Simone, Rebola, Nelson, van Woerden, Geeske M., Marinelli, Silvia, DiGregorio, David, Bacci, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086817/
https://www.ncbi.nlm.nih.gov/pubmed/25003184
http://dx.doi.org/10.1371/journal.pbio.1001903