Poly(A)-tail profiling reveals an embryonic switch in translational control

Poly(A) tails enhance the stability and translation of most eukaryotic mRNAs, but difficulties in globally measuring poly(A)-tail lengths have impeded greater understanding of poly(A)-tail function. Here, we describe poly(A)-tail length profiling by sequencing (PAL-seq) and apply it to measure tail...

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Detalles Bibliográficos
Autores principales: Subtelny, Alexander O., Eichhorn, Stephen W., Chen, Grace R., Sive, Hazel, Bartel, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086860/
https://www.ncbi.nlm.nih.gov/pubmed/24476825
http://dx.doi.org/10.1038/nature13007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086860/
https://www.ncbi.nlm.nih.gov/pubmed/24476825
http://dx.doi.org/10.1038/nature13007

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