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miR-196b-Mediated Translation Regulation of Mouse Insulin2 via the 5′UTR

The 5′ and the 3′ untranslated regions (UTR) of the insulin genes are very well conserved across species. Although microRNAs (miRNAs) are known to regulate insulin secretion process, direct regulation of insulin biosynthesis by miRNA has not been reported. Here, we show that mouse microRNA miR-196b...

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Detalles Bibliográficos
Autores principales: Panda, Amaresh C., Sahu, Itishri, Kulkarni, Shardul D., Martindale, Jennifer L., Abdelmohsen, Kotb, Vindu, Arya, Joseph, Jomon, Gorospe, Myriam, Seshadri, Vasudevan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086887/
https://www.ncbi.nlm.nih.gov/pubmed/25003985
http://dx.doi.org/10.1371/journal.pone.0101084