The Anoikis Effector Bit1 Displays Tumor Suppressive Function in Lung Cancer Cells

The mitochondrial Bit1 (Bcl-2 inhibitor of transcription 1) protein is a part of an apoptotic pathway that is uniquely regulated by integrin-mediated attachment. As an anoikis effector, Bit1 is released into the cytoplasm following loss of cell attachment and induces a caspase-independent form of ap...

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Detalles Bibliográficos
Autores principales: Yao, Xin, Jennings, Scott, Ireland, Shubha Kale, Pham, Tri, Temple, Brandi, Davis, Mya, Chen, Renwei, Davenport, Ian, Biliran, Hector
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086906/
https://www.ncbi.nlm.nih.gov/pubmed/25003198
http://dx.doi.org/10.1371/journal.pone.0101564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086906/
https://www.ncbi.nlm.nih.gov/pubmed/25003198
http://dx.doi.org/10.1371/journal.pone.0101564

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