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Therapeutic Effect of Nanogel-Based Delivery of Soluble FGFR2 with S252W Mutation on Craniosynostosis

Apert syndrome is an autosomal dominantly inherited disorder caused by missense mutations in fibroblast growth factor receptor 2 (FGFR2). Surgical procedures are frequently required to reduce morphological and functional defects in patients with Apert syndrome; therefore, the development of noninvas...

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Detalles Bibliográficos
Autores principales: Yokota, Masako, Kobayashi, Yukiho, Morita, Jumpei, Suzuki, Hiroyuki, Hashimoto, Yoshihide, Sasaki, Yoshihiro, Akiyoshi, Kazunari, Moriyama, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086955/
https://www.ncbi.nlm.nih.gov/pubmed/25003957
http://dx.doi.org/10.1371/journal.pone.0101693