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CTLA4 Variants and Haplotype Contribute Genetic Susceptibility to Myasthenia Gravis in Northern Chinese Population

BACKGROUND: Cytotoxic T lymphocyte-associated antigen-4 (CTLA4), a critical negative regulator of the T-cell response, has been considered a candidate for many autoimmune diseases. Evidence from Caucasians supported a genetic predisposition of CTLA4 to myasthenia gravis (MG), but the contribution in...

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Detalles Bibliográficos
Autores principales: Sun, Liang, Meng, Yunxiao, Xie, Yanchen, Zhang, Hua, Zhang, Zheng, Wang, Xiaoxia, Jiang, Bin, Li, Wei, Li, Yao, Yang, Ze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086970/
https://www.ncbi.nlm.nih.gov/pubmed/25003519
http://dx.doi.org/10.1371/journal.pone.0101986