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EPO Promotes Bone Repair through Enhanced Cartilaginous Callus Formation and Angiogenesis
Erythropoietin (EPO)/erythropoietin receptor (EPOR) signaling is involved in the development and regeneration of several non-hematopoietic tissues including the skeleton. EPO is identified as a downstream target of the hypoxia inducible factor-α (HIF-α) pathway. It is shown that EPO exerts a positiv...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087003/ https://www.ncbi.nlm.nih.gov/pubmed/25003898 http://dx.doi.org/10.1371/journal.pone.0102010 |