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EPO Promotes Bone Repair through Enhanced Cartilaginous Callus Formation and Angiogenesis

Erythropoietin (EPO)/erythropoietin receptor (EPOR) signaling is involved in the development and regeneration of several non-hematopoietic tissues including the skeleton. EPO is identified as a downstream target of the hypoxia inducible factor-α (HIF-α) pathway. It is shown that EPO exerts a positiv...

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Detalles Bibliográficos
Autores principales: Wan, Lin, Zhang, Fengjie, He, Qiling, Tsang, Wing Pui, Lu, Li, Li, Qingnan, Wu, Zhihong, Qiu, Guixing, Zhou, Guangqian, Wan, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087003/
https://www.ncbi.nlm.nih.gov/pubmed/25003898
http://dx.doi.org/10.1371/journal.pone.0102010