Aging and CaMKII Alter Intracellular Ca(2+) Transients and Heart Rhythm in Drosophila melanogaster

Aging is associated to disrupted contractility and rhythmicity, among other cardiovascular alterations. Drosophila melanogaster shows a pattern of aging similar to human beings and recapitulates the arrhythmogenic conditions found in the human heart. Moreover, the kinase CaMKII has been characterize...

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Detalles Bibliográficos
Autores principales: Santalla, Manuela, Valverde, Carlos A., Harnichar, Ezequiel, Lacunza, Ezequiel, Aguilar-Fuentes, Javier, Mattiazzi, Alicia, Ferrero, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087024/
https://www.ncbi.nlm.nih.gov/pubmed/25003749
http://dx.doi.org/10.1371/journal.pone.0101871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087024/
https://www.ncbi.nlm.nih.gov/pubmed/25003749
http://dx.doi.org/10.1371/journal.pone.0101871

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