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Aging and CaMKII Alter Intracellular Ca(2+) Transients and Heart Rhythm in Drosophila melanogaster
Aging is associated to disrupted contractility and rhythmicity, among other cardiovascular alterations. Drosophila melanogaster shows a pattern of aging similar to human beings and recapitulates the arrhythmogenic conditions found in the human heart. Moreover, the kinase CaMKII has been characterize...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087024/ https://www.ncbi.nlm.nih.gov/pubmed/25003749 http://dx.doi.org/10.1371/journal.pone.0101871 |