Effect of the Piperazine Unit and Metal-Binding Site Position on the Solubility and Anti-Proliferative Activity of Ruthenium(II)- and Osmium(II)- Arene Complexes of Isomeric Indolo[3,2-c]quinoline—Piperazine Hybrids

[Image: see text] In this study, the indoloquinoline backbone and piperazine were combined to prepare indoloquinoline–piperazine hybrids and their ruthenium- and osmium-arene complexes in an effort to generate novel antitumor agents with improved aqueous solubility. In addition, the position of the...

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Detalles Bibliográficos
Autores principales: Filak, Lukas K., Kalinowski, Danuta S., Bauer, Theresa J., Richardson, Des R., Arion, Vladimir B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087041/
https://www.ncbi.nlm.nih.gov/pubmed/24927493
http://dx.doi.org/10.1021/ic500825j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087041/
https://www.ncbi.nlm.nih.gov/pubmed/24927493
http://dx.doi.org/10.1021/ic500825j

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