A non-parametric approach for detecting gene-gene interactions associated with age-at-onset outcomes

BACKGROUND: Cox-regression-based methods have been commonly used for the analyses of survival outcomes, such as age-at-disease-onset. These methods generally assume the hazard functions are proportional among various risk groups. However, such an assumption may not be valid in genetic association st...

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Detalles Bibliográficos
Autores principales: Li, Ming, Gardiner, Joseph C, Breslau, Naomi, Anthony, James C, Lu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087128/
https://www.ncbi.nlm.nih.gov/pubmed/24986733
http://dx.doi.org/10.1186/1471-2156-15-79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087128/
https://www.ncbi.nlm.nih.gov/pubmed/24986733
http://dx.doi.org/10.1186/1471-2156-15-79

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