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A non-parametric approach for detecting gene-gene interactions associated with age-at-onset outcomes
BACKGROUND: Cox-regression-based methods have been commonly used for the analyses of survival outcomes, such as age-at-disease-onset. These methods generally assume the hazard functions are proportional among various risk groups. However, such an assumption may not be valid in genetic association st...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087128/ https://www.ncbi.nlm.nih.gov/pubmed/24986733 http://dx.doi.org/10.1186/1471-2156-15-79 |