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Wnt5a Evokes Cortical Axon Outgrowth and Repulsive Guidance by Tau Mediated Reorganization of Dynamic Microtubules

Wnt5a guides cortical axons in vivo by repulsion and in vitro evokes cortical axon outgrowth and repulsion by calcium signaling pathways. Here we examined the role of microtubule (MT) reorganization and dynamics in mediating effects of Wnt5a. Inhibiting MT dynamics with nocodazole and taxol abolishe...

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Detalles Bibliográficos
Autores principales: Li, Li, Fothergill, Thomas, Hutchins, B Ian, Dent, Erik W, Kali, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087151/
https://www.ncbi.nlm.nih.gov/pubmed/23818454
http://dx.doi.org/10.1002/dneu.22102