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Identification and validation of a novel microRNA-like molecule derived from a cytoplasmic RNA virus antigenome by bioinformatics and experimental approaches

BACKGROUND: It is generally believed that RNA virus replicating in the cell cytoplasm would not encode microRNAs (miRNAs) due to nucleus inaccessibility. Recent studies have described cytoplasmic RNA virus genome-derived miRNAs in West Nile virus (WNV) and Dengue virus (DENV). However, naturally occ...

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Detalles Bibliográficos
Autores principales: Shi, Jiandong, Duan, Zhiqing, Sun, Jing, Wu, Meini, Wang, Bin, Zhang, Jing, Wang, Haixuan, Hu, Ningzhu, Hu, Yunzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087238/
https://www.ncbi.nlm.nih.gov/pubmed/24981144
http://dx.doi.org/10.1186/1743-422X-11-121