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Structure of the LdcB LD-Carboxypeptidase Reveals the Molecular Basis of Peptidoglycan Recognition

Peptidoglycan surrounds the bacterial cytoplasmic membrane to protect the cell against osmolysis. The biosynthesis of peptidoglycan, made of glycan strands crosslinked by short peptides, is the target of antibiotics like β-lactams and glycopeptides. Nascent peptidoglycan contains pentapeptides that...

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Detalles Bibliográficos
Autores principales: Hoyland, Christopher N., Aldridge, Christine, Cleverley, Robert M., Duchêne, Marie-Clémence, Minasov, George, Onopriyenko, Olena, Sidiq, Karzan, Stogios, Peter J., Anderson, Wayne F., Daniel, Richard A., Savchenko, Alexei, Vollmer, Waldemar, Lewis, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087270/
https://www.ncbi.nlm.nih.gov/pubmed/24909784
http://dx.doi.org/10.1016/j.str.2014.04.015