A novel signaling pathway regulates colon cancer angiogenesis through Norrin

Norrin binds to the frizzled-4 receptor, stimulating canonical Wnt signaling. We investigate here the role of colorectal cancer (CRC) produced Norrin in endothelial cell growth, motility, and blood vessel formation, as well as the expression of the Norrin signaling pathway components in the CRC tumo...

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Detalles Bibliográficos
Autores principales: Planutis, Kestutis, Planutiene, Marina, Holcombe, Randall F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088094/
https://www.ncbi.nlm.nih.gov/pubmed/25005225
http://dx.doi.org/10.1038/srep05630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088094/
https://www.ncbi.nlm.nih.gov/pubmed/25005225
http://dx.doi.org/10.1038/srep05630

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