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Cooperativity and Equilibrium with FOXA1 Define the Androgen Receptor Transcriptional Program

The pioneering factor FOXA1 opens chromatin to facilitate androgen receptor (AR) binding to prostate-specific genes. How FOXA1 controls the AR cistrome, however, is incompletely understood. Here we show that AR directly binds chromatin through the androgen-response elements (AREs). FOXA1 is not requ...

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Detalles Bibliográficos
Autores principales: Jin, Hong-Jian, Zhao, Jonathan C., Wu, Longtao, Kim, Jung, Yu, Jindan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088269/
https://www.ncbi.nlm.nih.gov/pubmed/24875621
http://dx.doi.org/10.1038/ncomms4972