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Cooperativity and Equilibrium with FOXA1 Define the Androgen Receptor Transcriptional Program
The pioneering factor FOXA1 opens chromatin to facilitate androgen receptor (AR) binding to prostate-specific genes. How FOXA1 controls the AR cistrome, however, is incompletely understood. Here we show that AR directly binds chromatin through the androgen-response elements (AREs). FOXA1 is not requ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088269/ https://www.ncbi.nlm.nih.gov/pubmed/24875621 http://dx.doi.org/10.1038/ncomms4972 |