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High throughput screening identifies modulators of histone deacetylase inhibitors

BACKGROUND: Previous studies from our laboratory and others have demonstrated that in addition to altering chromatin acetylation and conformation, histone deacetylase inhibitors (HDACi) disrupt the acetylation status of numerous transcription factors and other proteins. A whole genome yeast deletion...

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Detalles Bibliográficos
Autores principales: Gaupel, Ann-Christin, Begley, Thomas, Tenniswood, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089024/
https://www.ncbi.nlm.nih.gov/pubmed/24968945
http://dx.doi.org/10.1186/1471-2164-15-528