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Transcriptional regulation and spatial interactions of head-to-head genes

BACKGROUND: In eukaryotic genomes, about 10% of genes are arranged in a head-to-head (H2H) orientation, and the distance between the transcription start sites of each gene pair is closer than 1 kb. Two genes in an H2H pair are prone to co-express and co-function. There have been many studies on bidi...

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Detalles Bibliográficos
Autores principales: Chen, Yunqin, Li, Yixue, Wei, Jia, Li, Yuan-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089025/
https://www.ncbi.nlm.nih.gov/pubmed/24962804
http://dx.doi.org/10.1186/1471-2164-15-519