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Comparison of peptide–major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells

Fluorochrome-conjugated peptide–major histocompatibility complex (pMHC) multimers are widely used for flow cytometric visualization of antigen-specific T cells. The most common multimers, streptavidin–biotin-based ‘tetramers’, can be manufactured readily in the laboratory. Unfortunately, there are l...

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Detalles Bibliográficos
Autores principales: Dolton, G, Lissina, A, Skowera, A, Ladell, K, Tungatt, K, Jones, E, Kronenberg-Versteeg, D, Akpovwa, H, Pentier, J M, Holland, C J, Godkin, A J, Cole, D K, Neller, M A, Miles, J J, Price, D A, Peakman, M, Sewell, A K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089154/
https://www.ncbi.nlm.nih.gov/pubmed/24673376
http://dx.doi.org/10.1111/cei.12339