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Optimization of High Grade Glioma Cell Culture from Surgical Specimens for Use in Clinically Relevant Animal Models and 3D Immunochemistry

Glioblastomas, the most common and aggressive form of astrocytoma, are refractory to therapy, and molecularly heterogeneous. The ability to establish cell cultures that preserve the genomic profile of the parental tumors, for use in patient specific in vitro and in vivo models, has the potential to...

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Detalles Bibliográficos
Autores principales: Hasselbach, Laura A., Irtenkauf, Susan M., Lemke, Nancy W., Nelson, Kevin K., Berezovsky, Artem D., Carlton, Enoch T., Transou, Andrea D., Mikkelsen, Tom, deCarvalho, Ana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089397/
https://www.ncbi.nlm.nih.gov/pubmed/24429465
http://dx.doi.org/10.3791/51088