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Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars

Background. Neuropilin-1 (NRP-1) is a multidomain membrane protein with soluble isoforms interacting with a complex network of other membrane receptors, their respective ligands and heparan sulfate (HS). It is involved in the development of vasculature, neural patterning, immunological responses and...

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Detalles Bibliográficos
Autores principales: Uniewicz, Katarzyna A., Ori, Alessandro, Ahmed, Yassir A., Yates, Edwin A., Fernig, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089425/
https://www.ncbi.nlm.nih.gov/pubmed/25024924
http://dx.doi.org/10.7717/peerj.461