Cargando…

Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars

Background. Neuropilin-1 (NRP-1) is a multidomain membrane protein with soluble isoforms interacting with a complex network of other membrane receptors, their respective ligands and heparan sulfate (HS). It is involved in the development of vasculature, neural patterning, immunological responses and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Uniewicz, Katarzyna A., Ori, Alessandro, Ahmed, Yassir A., Yates, Edwin A., Fernig, David G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2014
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089425/ https://www.ncbi.nlm.nih.gov/pubmed/25024924 http://dx.doi.org/10.7717/peerj.461

Ejemplares similares

Introduction to the Molecules Special Edition Entitled ‘Heparan Sulfate and Heparin: Challenges and Controversies’: Some Outstanding Questions in Heparan Sulfate and Heparin Research
por: Yates, Edwin A, et al.
Publicado: (2019)

By-Products of Heparin Production Provide a Diverse Source of Heparin-like and Heparan Sulfate Glycosaminoglycans
por: Taylor, Sarah L., et al.
Publicado: (2019)

Diverse Roles of Heparan Sulfate and Heparin in Wound Repair
por: Olczyk, Pawel, et al.
Publicado: (2015)

Polymers Inspired by Heparin and Heparan Sulfate for Viral Targeting
por: Hoffmann, Miriam, et al.
Publicado: (2022)

The Challenge of Modulating Heparan Sulfate Turnover by Multitarget Heparin Derivatives
por: Veraldi, Noemi, et al.
Publicado: (2020)

Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates
por: Karlsson, Richard, et al.
Publicado: (2021)

The Solution Structure of Heparan Sulfate Differs from That of Heparin: IMPLICATIONS FOR FUNCTION
por: Khan, Sanaullah, et al.
Publicado: (2013)

Chemoenzymatic synthesis of heparan sulfate and heparin oligosaccharides and NMR analysis: paving the way to a diverse library for glycobiologists
por: Zhang, Xing, et al.
Publicado: (2017)

Panels of chemically-modified heparin polysaccharides and natural heparan sulfate saccharides both exhibit differences in binding to Slit and Robo, as well as variation between protein binding and cellular activity
por: Ahmed, Yassir A., et al.
Publicado: (2016)

Small molecule antagonists of cell-surface heparan sulfate and heparin–protein interactions
por: Weiss, Ryan J., et al.
Publicado: (2015)

Structure-Activity Relationships of Bioengineered Heparin/Heparan Sulfates Produced in Different Bioreactors
por: Kim, Ha Na, et al.
Publicado: (2017)

The neutralization of heparan sulfate by heparin-binding copolymer as a potential therapeutic target
por: Kalaska, Bartlomiej, et al.
Publicado: (2019)

Noncovalent hyaluronan crosslinking by TSG-6: Modulation by heparin, heparan sulfate, and PRG4
por: Sin, Yun Jin Ashley, et al.
Publicado: (2022)

Heparin Mimetics: Their Therapeutic Potential
por: Mohamed, Shifaza, et al.
Publicado: (2017)

Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor
Publicado: (1990)

Molecular Interactions between Complement Factor H and Its Heparin and Heparan Sulfate Ligands
por: Perkins, Stephen J., et al.
Publicado: (2014)

Heparin and Liver Heparan Sulfate Can Rescue Hepatoma Cells from Topotecan Action
por: Dudás, József, et al.
Publicado: (2014)

Heparin/Heparan Sulfate Proteoglycans Glycomic Interactome in Angiogenesis: Biological Implications and Therapeutical Use
por: Chiodelli, Paola, et al.
Publicado: (2015)

Soluble Heparin and Heparan Sulfate Glycosaminoglycans Interfere with Sonic Hedgehog Solubilization and Receptor Binding
por: Manikowski, Dominique, et al.
Publicado: (2019)

Can We Produce Heparin/Heparan Sulfate Biomimetics Using “Mother-Nature” as the Gold Standard?
por: Farrugia, Brooke L., et al.
Publicado: (2015)

Heparin, Heparan Sulphate and the TGF-β Cytokine Superfamily
por: Rider, Chris C., et al.
Publicado: (2017)

Heparin-binding protein as a novel biomarker for sepsis-related acute kidney injury
por: Pajenda, Sahra, et al.
Publicado: (2020)

Heparin binding preference and structures in the fibroblast growth factor family parallel their evolutionary diversification
por: Li, Yong, et al.
Publicado: (2016)

On the Specificity of Heparin/Heparan Sulfate Binding to Proteins. Anion-Binding Sites on Antithrombin and Thrombin Are Fundamentally Different
por: Mosier, Philip D., et al.
Publicado: (2012)

Tunable Heparan Sulfate Mimetics for Modulating Chemokine Activity
por: Sheng, Gloria J., et al.
Publicado: (2013)

Involvement of cochlin binding to sulfated heparan sulfate/heparin in the pathophysiology of autosomal dominant late-onset hearing loss (DFNA9)
por: Honda, Tomoko, et al.
Publicado: (2022)

Glycomics Approaches for the Bioassay and Structural Analysis of Heparin/Heparan Sulphates
por: Puvirajesinghe, Tania M., et al.
Publicado: (2012)

Heparin, Heparan Sulphate and Sepsis: Potential New Options for Treatment
por: Hogwood, John, et al.
Publicado: (2023)

Aggregation Kinetics and Filament Structure of a Tau Fragment Are Influenced by the Sulfation Pattern of the Cofactor Heparin
por: Townsend, David, et al.
Publicado: (2020)

Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 Glomerulopathies
por: Loeven, Markus A., et al.
Publicado: (2021)

Heparin Mimetics and Their Impact on Extracellular Matrix Protein Assemblies
por: Heide, Fabian, et al.
Publicado: (2023)

Low sulfated heparins target multiple proteins for central nervous system repair
por: McCanney, George A., et al.
Publicado: (2018)

Understanding Dermatan Sulfate−Heparin Cofactor II Interaction through Virtual Library Screening
por: Raghuraman, Arjun, et al.
Publicado: (2010)

The Heparan and Heparin Metabolism Pathway is Involved in Regulation of Fatty Acid Composition
por: Jiang, Zhihua, et al.
Publicado: (2011)

Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing
por: Jiang, Lan, et al.
Publicado: (2022)

New Applications of Heparin and Other Glycosaminoglycans
por: Lima, Marcelo, et al.
Publicado: (2017)

Heparin and heparan sulfate proteoglycans promote HIV-1 p17 matrix protein oligomerization: computational, biochemical and biological implications
por: Bugatti, Antonella, et al.
Publicado: (2019)

Heparin-binding EGF-like growth factor stimulation of smooth muscle cell migration: dependence on interactions with cell surface heparan sulfate
Publicado: (1993)

Binding of Subdomains 1/2 of PfEMP1-DBL1α to Heparan Sulfate or Heparin Mediates Plasmodium falciparum Rosetting
por: Angeletti, Davide, et al.
Publicado: (2015)

Sulfonated Nonsaccharide Heparin Mimetics Are Potent and Noncompetitive Inhibitors of Human Neutrophil Elastase
por: Al-Horani, Rami A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f66vv0ajqqr9mqjsl1dkrccjd2