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Rapamycin Attenuated Cardiac Hypertrophy Induced by Isoproterenol and Maintained Energy Homeostasis via Inhibiting NF-κB Activation

Rapamycin, also known as sirolimus, is an immunosuppressant drug used to prevent rejection organ (especially kidney) transplantation. However, little is known about the role of Rapa in cardiac hypertrophy induced by isoproterenol and its underlying mechanism. In this study, Rapa was administrated in...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Zeng, Siyu, Zou, Jian, Chen, Yanfang, Yue, Zhongbao, Gao, Ying, Zhang, Luankun, Cao, Weiwei, Liu, Peiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089551/
https://www.ncbi.nlm.nih.gov/pubmed/25045214
http://dx.doi.org/10.1155/2014/868753